BRN 0477606

BRN 0477606 - Names and Identifiers

Name	4-Hydroxy-1-phenethylpiperidine-4-carbonitrile
Synonyms	BRN 0477606 4-Hydroxy-1-phenethylisonipecotonitrile Isonipecotonitrile, 4-hydroxy-1-phenethyl- 5-22-05-00027 (Beilstein Handbook Reference) 4-Hydroxy-1-phenethylpiperidine-4-carbonitrile 4-Hydroxy-1-phenethyl-4-piperidinecarbonitrile 4-hydroxy-1-phenethylpiperidine-4-carbonitrile 4-Hydroxy-1-(2-phenylethyl)-4-piperidinecarbonitrile 4-hydroxy-1-(2-phenylethyl)piperidine-4-carbonitrile 4-Piperidinecarbonitrile,4-hydroxy-1-(2-phenylethyl)-
CAS	23804-59-3
EINECS	245-891-9
InChI	InChI=1/C14H18N2O/c15-12-14(17)7-10-16(11-8-14)9-6-13-4-2-1-3-5-13/h1-5,17H,6-11H2

BRN 0477606 - Physico-chemical Properties

Molecular Formula	C14H18N2O
Molar Mass	230.31
Density	1.14
Melting Point	93℃
Boling Point	419.1±45.0 °C(Predicted)
Flash Point	207.2°C
Vapor Presure	9.01E-08mmHg at 25°C
pKa	11.01±0.20(Predicted)
Refractive Index	1.582

BRN 0477606 - Introduction

It is an organic compound with the chemical formula C16H18N2O. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid.
-Melting point: About 117-121 degrees Celsius.
-Solubility: Soluble in chloroform, methanol and dichloromethane, slightly soluble in ethanol, almost insoluble in water.

Use:
-is an important synthetic intermediate, which has certain application in the field of drug research.
-It can be used to synthesize a variety of biologically active molecules, such as anti-tumor drugs, analgesic drugs, etc.

Method:
-There are many preparation methods for it. One commonly used method is to start with 4-hydroxy-1-phenylethyl-piperidine:
-First, 4-hydroxy-1-phenylethyl-piperidine is reacted with triethylamine to generate the corresponding salt.
-Then, treat the salt with hydrocyanic acid to form quartz.

Safety Information:
-It has limited toxicity information and therefore requires careful handling and use.
-It may be irritating to the eyes, skin and respiratory system. Avoid direct contact with skin and eyes.
-During use, appropriate laboratory safety measures should be taken, such as wearing laboratory gloves, goggles and protective clothing, and ensuring good ventilation conditions.
-If inhaled or ingested, seek medical attention immediately.

Last Update：2024-04-09 21:01:54